[News & Trends]:Differences in chemical methods between acetyl chloride and acetic acid

Acetyl chloride and acetic acid are two common organic compounds that have significant differences in chemical methods and properties. This article will provide a detailed analysis of the differences between acetyl chloride and acetic acid from three aspects: molecular structure, preparation methods, and chemical properties


1、 The chemical formula of acetic acid is CH3COOH, which is an acidic substance. The chemical formula of acetyl chloride is CH3COCl, which is an acylation reagent and belongs to a type of acyl chloride complex. The main difference in molecular structure between the two is that one hydroxyl OH in ethyl ester is replaced by chlorine atom Cl, forming an acyl chloride structure


2、 The conventional preparation methods for acetic acid include acetic acid bacteria method, ethylene synthesis method, and acetaldehyde oxidation method. Among them, the acetic acid bacteria method is the most commonly used method for preparing acetic acid. The preparation method of acetyl chloride is mainly achieved by adding chlorine gas or acyl chloride compounds to acetic acid and reacting with it


3、 Chemical properties: Acetyl chloride and acetic acid have significant differences in chemical properties. Acetic acid is acidic and can react with bases to form acetate salts. It can also remove a hydroxyl group to form acetaldehyde. Acetyl chloride is a strong acidic reagent that is corrosive and can react with nucleophilic reagents such as alcohols and amines to produce acylation products. In addition, acetyl chloride acetate can also react with amines to generate corresponding amide compounds


In summary, there are significant differences in molecular structure, preparation methods, and chemical properties between acetyl chloride acetate and acetic acid. By understanding these differences, we can better apply them for different purposes in laboratories and industrial production.