HQEE (Hydrogenated ethyl ethyl quinine) is an important raw material for the production of chemicals, which is widely used in the fields of pharmaceuticals, pesticides and spices. A manufacturing method of HQEE will be described below.
I. Raw materials and equipment
1. Raw materials: ethyl ethyl quinine (EEQ), hydrogen, catalyst.
2. Equipment: high-pressure reactor, stirring device, cooling system, separation device, storage tank and so on.
2. Manufacturing steps
1. Catalyst preparation: Add the selected catalyst to the appropriate amount of solvent according to a certain proportion, stir well, and then dry to produce catalyst for spare.
2. Charging: Ethyl ethyl quinine was added into a high-pressure reactor, and then hydrogen was passed in, maintaining a certain pressure and temperature.
3. Hydrogenation reaction: Under stirring, make ethyl ethyl quinine and hydrogen gas fully contact, the hydrogenation reaction occurs, to produce HQEE.
4. Cooling and separation: After the reaction is finished, the mixture in the reactor is cooled down to a suitable temperature, and the HQEE is separated from the un-reacted raw materials and catalyst by the separation device.
5. Purification and drying: Purify and dry the HQEE obtained by separation to obtain high quality HQEE products.
3. Precautions
1. Strictly control the reaction temperature and pressure to ensure that the reaction is carried out under safe and effective conditions.
2. The choice of catalyst and the amount of catalyst used have an important influence on the reaction rate and HQEE yield, and need to be optimized according to the actual situation.
3. During the separation and purification process, contact between HQEE and other impurities should be avoided so as not to affect the product quality.
4. Yield and quality control
1. Yield: yield is affected by many factors, such as purity of raw materials, catalyst activity, reaction conditions, etc.. In order to improve the yield, the factors need to be optimized.
2. Quality control: Through quality testing of HQEE products, such as the determination of melting point, boiling point, purity and other indexes, to ensure that the products meet the relevant standards.
V. Environmental protection and safety measures
1. Wastewater treatment: Properly treat the wastewater generated in the production process to avoid pollution to the environment.
2. Waste gas treatment: Collect and treat the waste gas produced in the reaction process to reduce air pollution.
3. Safety protection: Strengthen the safety protection measures of the production equipment and improve the safety awareness of the employees to ensure the production process is safe and smooth.
VI. Optimization and Improvement
1. Modify or screen the catalyst to improve the activity and selectivity of the catalyst, and then improve the yield of HQEE.
2. Optimize the reaction conditions, such as temperature, pressure, stirring speed, etc., to improve the reaction speed and product quality.
3. Employing novel separation and purification techniques to improve the purity and yield of HQEE.
In short, the manufacturing method of HQEE needs to consider comprehensively the raw materials, equipment, manufacturing steps, precautions, yield and quality control, environmental protection and safety measures, as well as optimization and improvement, in order to ensure the quality of the product and the smooth production. Meanwhile, with the continuous progress of science and technology, new manufacturing methods and technologies need to be explored to improve the production efficiency and economic benefits of HQEE.
