Ethyl difluorobromoacetate is an important raw material for chemical production, widely used in medicine, pesticide, liquid crystal materials and other fields. In this article, we will introduce the manufacturing method of ethyl difluorobromoacetate, including raw material preparation, reaction steps, post-treatment and other aspects.
I. Raw material preparation
The following raw materials are required for the manufacture of ethyl difluorobromoacetate: difluoroacetic acid, sodium bromide, ethanol, sulfuric acid. Among them, difluoroacetic acid and sodium bromide are the main reactants, ethanol is used as a solvent, and sulfuric acid is used as a catalyst.
II. Reaction steps
1. Difluoroacetic acid and sodium bromide are added to ethanol and stirred well to obtain a mixed solution.
2. Sulfuric acid was added to the mixed solution, and the reaction temperature was controlled at 50-60°C for about 2-3 hours.
3. At the end of the reaction, the reaction solution was poured into ice water and the solid product was precipitated.
4. The solid product was obtained by filtration and recrystallized with ethanol to obtain ethyl difluorobromoacetate with higher purity.
3. Post-treatment
1. The obtained ethyl difluorobromoacetate was tested for purity to ensure that its purity meets the requirements.
2. Treat the waste liquid and waste gas in the production process to ensure the environmental protection requirements.
4. Precautions
1. Strictly control the reaction temperature and time in the production process to avoid by-products.
2. Regular maintenance and repair of production equipment and pipelines to ensure production safety and stability.
In conclusion, the method of manufacturing ethyl difluorobromoacetate requires strict control of reaction conditions and raw material quality to ensure product purity and production safety. At the same time, it is also necessary to dispose of the waste in the production process to protect the environment.
