Dihydroxymethylpropionic acid (DMPA) is an important chemical raw material, widely used in synthetic resins, plastics, fibers, pharmaceuticals, pesticides and other fields. The following is the manufacturing method of DMPA:
I. Raw material preparation
1. Propionic acid: propionic acid is the main raw material for manufacturing DMPA, which can be obtained by cracking petrochemical raw material or fermentation method.
2. Formaldehyde: Formaldehyde, as another raw material for the reaction, can be obtained by oxidation or methanol dehydrogenation.
3. Sodium hydroxide: It is used to adjust the pH of the reaction system and promote the reaction.
II. Synthesis reaction
1. Add propionic acid and formaldehyde into the reaction kettle according to a certain molar ratio and stir well.
2. Add sodium hydroxide to the reaction system and adjust the pH to an alkaline environment to promote the hydroxymethylation reaction between formaldehyde and propionic acid.
3. Under a certain temperature and pressure, keep the reaction for a certain time, so that propionic acid and formaldehyde fully react to form dihydroxymethyl propionic acid.
3. Post-treatment
1. After the reaction, cool the reaction solution to room temperature and adjust the pH to neutral or acidic.
2. Remove impurities and by-products from the reaction system by centrifugation and filtration.
3. The filtrate was distilled to recover the unreacted raw materials and obtain the crude dihydroxymethylpropionic acid with high purity.
4. Purification
1. Further purify the crude dihydroxymethylpropionic acid to improve the product quality.
2. Use recrystallization and distillation to remove impurities and by-products in the product.
3. After passing the test, obtain the high purity dihydroxymethylpropionic acid product.
The above is an overview of the manufacturing method of dihydroxymethylpropionic acid, and the process parameters need to be adjusted according to the actual situation during the specific operation to ensure the quality and yield of the product. At the same time, it is necessary to pay attention to safety in the production process and comply with relevant regulations and rules to ensure environmental protection and sustainable development.
