Folone is an important raw material for the production of chemicals, which is widely used in the fields of pharmaceuticals, pesticides, spices and so on. In this article, we will introduce the manufacturing method of Folzone, including raw material preparation, reaction steps, post-treatment and other aspects.
I. Raw material preparation
The following raw materials are needed to manufacture Folzone: phenol, acetone, sodium hydroxide. Among them, the ratio of phenol and acetone is 1:1, and the amount of sodium hydroxide is 10% of the mass of phenol.
2. Reaction steps
1. Add phenol and acetone into the reactor according to the proportion and stir well.
2. Slowly add sodium hydroxide solution under stirring, control the reaction temperature at 60-70°C, and the reaction time is about 2 hours.
3. At the end of the reaction, the reaction solution was cooled down to room temperature, and the crystallization of Foerone was precipitated.
3. Post-treatment
1. The precipitated Buddhaone crystals were filtered and washed with a small amount of cold water to obtain Buddhaone crude product.
2. Add the crude product of Buddha Ketone into the distillation kettle, carry out vacuum distillation, collect the fraction with boiling point of 170-175°C, and get the finished product of Buddha Ketone.
4. Precautions
1. During the reaction process, the reaction temperature and the addition rate of sodium hydroxide should be strictly controlled to avoid side reaction or coking phenomenon.
2. In the post-treatment process, the airtightness and vacuum degree of the equipment should be ensured to avoid contamination or oxidation of the finished product of Foerone.
V. Manufacturing Advantages
The manufacturing method of Buddha Ketone has the advantages of easy to obtain raw materials, simple operation, high yield, and at the same time, it can get the finished product of Buddha Ketone with high purity, which has a better application prospect.
In short, the manufacturing method of Foerone needs to master certain chemical knowledge and skills, and at the same time, it needs to strictly abide by the laboratory safety operation regulations to ensure the smooth progress of the manufacturing process and the safety of personnel.
