Manufacturing method of ethyl phenylcyanoacetate
Ethyl phenylcyanoacetate is an important organic chemical raw material, which is widely used in the fields of medicine, pesticide, dye and so on. In this article, we will introduce the manufacturing method of ethyl phenylcyanoacetate, including raw material preparation, reaction steps, post-treatment and precautions.
I. Raw material preparation
1. Phenylacetic acid: Phenylacetic acid is the main raw material for the preparation of ethyl phenylcyanoacetate, which should have high purity to ensure the quality of the product.
2. Sodium cyanide: Sodium cyanide is used as a source of cyanide to react with phenylacetic acid to form phenylcyanoacetic acid.
3. Ethanol: Ethanol is used as solvent and reactant to react with phenylcyanoacetic acid to form ethyl phenylcyanoacetate.
2. Reaction steps
1. Add phenylacetic acid into the reactor, then add appropriate amount of ethanol and stir well.
2. Slowly add sodium cyanide aqueous solution under stirring, control the dosing speed and keep the reaction temperature within a certain range.
3. After the addition is completed, continue stirring for a certain period of time, so that the reaction is fully carried out.
4. At the end of the reaction, the reaction solution is cooled to room temperature and the solid product is precipitated.
5. The finished product of ethyl phenylcyanoacetate is obtained by filtering, washing, drying and other operations.
III. Post-treatment
1. Waste liquid treatment: the waste liquid generated during the reaction should be properly treated to avoid pollution to the environment. Oxidation reduction, precipitation and other methods can be taken for treatment.
2. Waste gas treatment: Harmful gases may be generated during the reaction process, which should be absorbed, burned and other treatments to ensure safe production.
4. Precautions
1. Strictly control the speed of adding materials to prevent the reaction from being too intense, which may cause safety accidents.
2. Stirring should be maintained during the reaction process to avoid deposition of raw materials and affect the reaction effect.
3. Operators should do a good job of personal protection to avoid contact with toxic and harmful substances.
4. The production process should follow the relevant safety regulations to ensure production safety.
In conclusion, the manufacturing method of ethyl phenylcyanoacetate requires strict control of reaction conditions to ensure product quality and production safety. Through reasonable raw material preparation, reaction steps and post-treatment operations, high quality ethyl phenylcyanoacetate can be prepared to support the development of related fields.
