Methyl tert-butyl acetophenone (MTBE) is an important organic chemical raw material, which is widely used in the fields of medicine, pesticide and spice. This article will introduce the manufacturing method of methyl tert-butyl acetophenone, including raw material selection, reaction principle, production process, equipment selection and other aspects.
I. Raw material selection
The raw materials for the manufacture of methyl tert-butyl acetophenone are mainly acetophenone and isobutylene. Among them, acetophenone is a common organic compound, which can be produced by the reaction of benzene and acetic anhydride. Isobutene, on the other hand, can be obtained by methods such as naphtha cracking or propylene dimerization.
II. Reaction Principle
The manufacture of methyl tert-butyl acetophenone is mainly through the alkylation reaction between acetophenone and isobutene under the action of an acidic catalyst to produce methyl tert-butyl acetophenone. The reaction equation is as follows:
C6H5COCH3 + CH2=C(CH3)2 → C6H5COCH2C(CH3)3
III. Manufacturing process
The manufacturing process of methyl tert-butyl acetophenone mainly consists of the following steps:
1. Preparation of catalyst: Acidic catalysts, such as sulphuric acid or acidic ion-exchange resin, are loaded into the reactor.
2. Mixing of raw materials: Mix acetophenone and isobutylene in a certain proportion and feed them into the reactor.
3. Reaction: Under the action of catalyst, acetophenone and isobutene undergo alkylation reaction to produce methyl tert-butyl acetophenone.
4. Separation and purification: After the reaction, the reaction liquid is separated and purified to obtain methyl tert-butyl acetophenone with high purity.
4. Equipment selection
The production of methyl tert-butyl acetophenone requires the use of reactors, mixers, separators and other equipment. When selecting the equipment, it is necessary to make comprehensive consideration according to the production scale, raw material characteristics, product requirements and other factors. At the same time, it is also necessary to pay attention to the material, sealing, corrosion resistance and other requirements of the equipment to ensure the reliability and stability of the equipment.
V. Precautions
In the production process of methyl tert-butyl acetophenone, the following matters need to be paid attention to:
1. Control the proportion of raw materials and reaction temperature to ensure the smooth progress of the reaction and the purity of the product.
2. Regularly check the operation and maintenance of the equipment to ensure the normal operation and service life of the equipment.
3. Strengthen the safety management of the production site to ensure the safety and reliability of the production process.
In conclusion, the manufacture of methyl tert-butyl acetophenone requires good knowledge and skills in raw material selection, reaction principle, production process, equipment selection, etc. Meanwhile, it needs to strengthen the production management and safety management in order to ensure the quality of the product and the safety of the production.
