Butyl tert-Butyl Phenyl Ketone (BTBP) is an important raw material for the production of chemicals, which is widely used in the fields of fine chemicals, pharmaceuticals and pesticides. In this paper, we will introduce the manufacturing method of Butyl tert-Butyl Phenyl Ketone, including raw material preparation, reaction process, and post-treatment.
I. Raw material preparation
The main raw materials for manufacturing butyl tert-butyl acetophenone are acetophenone, isobutylene and tert-butanol. Among them, acetophenone can be produced by reacting benzene with acetic anhydride, isobutene can be produced by naphtha cracking or propylene dimerization, and tert-butanol can be produced by isobutylene hydration.
II. Reaction process
1. Foucault acylation reaction
Foucault acylation reaction is carried out between acetophenone and isobutene in the presence of acid catalyst (such as sulfuric acid, hydrofluoric acid, etc.) to produce tert-butyl acetophenone. The reaction is exothermic, and the reaction temperature needs to be controlled, while the amount and type of catalyst need to be paid attention to, in order to avoid the generation of too many by-products.
2. Alcoholysis reaction
Alcoholysis of tert-butyl acetophenone with tert-butanol was carried out in the presence of acidic catalyst to produce butyl tert-butyl acetophenone. The reaction is also exothermic and the reaction temperature needs to be controlled, while the amount and type of catalyst need to be paid attention to in order to ensure the selectivity and yield of the reaction.
Three, post-treatment
After the reaction is finished, post-treatment is needed, including distillation, washing, drying and other steps, in order to obtain pure butyl tert-butyl acetophenone products. Among them, distillation is to separate the unreacted raw materials and by-products, washing is to remove the residual catalyst and impurities, and drying is to remove water to ensure the quality of the product.
4. Precautions
1. In the operation process, attention needs to be paid to control the reaction temperature and the amount of catalyst to avoid the generation of by-products and the corrosion of equipment.
2. In the post-treatment process, the purity and quality of the products need to be ensured to avoid the influence on the downstream products.
3. In the production process, safety needs to be taken care of to avoid fire, explosion and other accidents.
In conclusion, the manufacturing method of butyl tert-butyl acetophenone requires several steps, including raw material preparation, reaction process and post-treatment. During the process, attention needs to be paid to controlling the reaction conditions and operating parameters to ensure the quality and yield of the product. Meanwhile, attention also needs to be paid to safety and production environmental protection in order to avoid the impact on personnel and the environment.
